Th17 cells

Marker Expression

Common

  • CD4
    Expression: +
    Suggested markerSuggested
  • CD194 (CCR4)
    Expression: +
    Citations:
    Suggested markerSuggested
  • IL-17
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
    Suggested markerSuggested
  • IL23R
    Expression: +
    Citations:
    Suggested markerSuggested
  • RORγT (RORC)
    Expression: +
    Localization: nuclear
    Citations:
    Suggested markerSuggested
  • CD8a
    Expression: -
  • CD161 (CD61)
    Expression: +
    Citations:
  • CD196 (CCR6)
    Expression: +
    Citations:
  • IL-9
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
  • IL-21
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
  • IL-22
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
  • IRF4
    Expression: +
    Localization: nuclear
    Citations:

Other Notes

Naive CD4+ T cells differentiate into Th17 cells in the presence of IL-6, IL-1β, and TGF-β.