Th17 cells Marker ExpressionIL-17 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]Required markerRequiredCD4 Expression: +Required markerRequiredRORγT (RORC) Expression: + Localization: intracellularCitations:[1]Required markerRequiredIRF4 Expression: + Localization: intracellularCitations:[1]Suggested markerSuggestedCD194 (CCR4) Expression: +Citations:[1]Suggested markerSuggestedIL23R Expression: +Citations:[1]Suggested markerSuggestedCD196 (CCR6) Expression: +Citations:[1]CD161 Expression: +Citations:[1]IL-9 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]CD8a Expression: -IL-21 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]IL-22 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]Cell/subset InformationTh17 cells promote immunity at mucosal barriers.Other NotesNaive CD4+ T cells differentiate into Th17 cells in the presence of IL-6, IL-1β, and TGF-β.AliasesT helper type 17TagsT helper lymphocyteT lymphocytelymphoidhematopoieticmesodermInformationCreated Michael Lehrke2025-04-12, 05:45:26 UTC
