Th9 cells Marker ExpressionCD4 Expression: +Required markerRequiredSPI1 (PU.1) Expression: + Localization: intracellularCitations:[1]Required markerRequiredIRF4 Expression: + Localization: intracellularCitations:[1]Required markerRequiredIL-9 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1][2]Required markerRequiredIL-21 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]Suggested markerSuggestedCD8a Expression: -Cell/subset InformationTh9 cells promote tissue inflammation and promote immune responses against parasites.Other NotesNaive CD4+ T cells differentiate into Th9 cells in the presence of IL-4 and TGF-β.AliasesT helper type 9TagsT helper lymphocyteT lymphocytelymphoidhematopoieticmesodermInformationCreated Michael Lehrke2025-04-12, 05:38:10 UTCUpdated Michael Lehrke2025-04-12, 05:46:17 UTC