Cytotoxic T cells (CD8+ T cells) Marker ExpressionCommonCD8a Expression: +Suggested markerSuggestedGranzyme B (GZMB) Expression: + Analysis strategy: Upon activationSuggested markerSuggestedIFNγ (IFNG) Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]Suggested markerSuggestedPerforin (PRF1) Expression: + Analysis strategy: Upon activationSuggested markerSuggestedCD4 Expression: -CD183 (CXCR3) Expression: +Citations:[1]Eomesodermin (EOMES) Expression: + Localization: nuclearCitations:[1]IL-2 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]IRF4 Expression: + Localization: nuclearCitations:[1]STAT4 Expression: + Localization: intracellularCitations:[1]TBET (TBX21) Expression: + Localization: nuclearCitations:[1][2]TNFα Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]AliasesCD8+ T cellsCD8+ T lymphocytesCytotoxic T lymphocytesTc1 cellsTagsT lymphocytelymphoidhematopoieticmesodermInformationCreated Michael Lehrke2025-04-13, 23:01:50 UTCUpdated Michael Lehrke2025-11-07, 02:24:26 UTCApproved Michael Lehrke2025-11-07, 02:24:26 UTC