Th2 cells

Marker Expression

  • GATA3
    Expression: +
    Localization: intracellular
    Citations:
    Required markerRequired
  • CD4
    Expression: +
    Required markerRequired
  • CD196 (CCR6)
    Expression: -
    Citations:
    Suggested markerSuggested
  • IL-5
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
    Suggested markerSuggested
  • CD294 (CRTH2)
    Expression: +
    Citations:
    Suggested markerSuggested
  • CD194 (CCR4)
    Expression: +
    Citations:
    Suggested markerSuggested
  • IL-13
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
  • TNFα
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
  • CD8a
    Expression: -
  • IRF4
    Expression: +
    Localization: intracellular
    Citations:
  • IL-4
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:
  • IL-9
    Expression: +
    Localization: secreted
    Citations:
  • IL-10
    Expression: +
    Localization: secreted
    Analysis strategy: Upon stimulation
    Citations:

Cell/subset Information

Th1 cells promote immune responses against extracellular pathogens such as parasites and bacteria.

Other Notes

Naive CD4+ T cells differentiate into Th2 cells in the presence of IL-4.