Regulatory T cells (Tregs) Marker ExpressionCommonFOXP3 Expression: + Localization: nuclearCitations:[1]Required markerRequiredCD4 Expression: +Suggested markerSuggestedCD25 (IL-2RA) Expression: +Citations:[1]Suggested markerSuggestedIL-10 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]Suggested markerSuggestedTGF-β Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]Suggested markerSuggestedCD8a Expression: -CD152 (CTLA-4) Expression: +Citations:[1]Cell/subset InformationCD4 T helper subset that modulates immune responses and maintains tolerance to self-antigens, preventing autoimmunity.AliasesTregsNatural TregsnTregsRegulatory T lymphocytesSuppressor T cellsSuppressor T lymphocytesTagsT helper lymphocyteT lymphocytelymphoidhematopoieticmesodermInformationCreated Michael Lehrke2025-04-12, 20:50:08 UTCUpdated Michael Lehrke2025-11-06, 05:15:27 UTCApproved Michael Lehrke2025-11-06, 05:15:27 UTC