Kupffer cells (KC) Marker ExpressionCommonCD45 Expression: +/-Citations:[1]Suggested markerSuggestedCD68 Expression: +Citations:[1]Suggested markerSuggestedCD284 (TLR4) Expression: +Citations:[1]Suggested markerSuggestedCX3CR1 Expression: -Citations:[1]Suggested markerSuggestedMouseF4/80 (ADGRE1) Expression: ++Citations:[1][2]Required markerRequiredITGAM (CD11b) Expression: ++Citations:[1][2]Required markerRequiredCLEC4F Expression: +Citations:[1]Suggested markerSuggestedLy6C Expression: -Citations:[1]Suggested markerSuggestedLy6G Expression: -Citations:[1]Suggested markerSuggestedCD11c (ITGAX) Expression: +/-Citations:[1]TIM4 (TIM4D) Expression: +Citations:[1]HumanCD14 Expression: +++Citations:[1][2]Required markerRequiredCD32 Expression: +/-Citations:[1]Required markerRequiredCell/subset InformationLiver-resident macrophages derived from the embryonic yolk sac. These cells filter blood from the hepatic portal system. Kupffer cells are able to self-renew, produce inflammatory cytokines, and recycle hemoglobin.AliasesKCKupffer Browicz cellsStellate macrophagesTagsmonocytemyelocytemyeloidhematopoieticmesodermInformationCreated Michael Lehrke2025-04-16, 01:21:12 UTCUpdated Michael Lehrke2025-04-16, 02:00:19 UTCApproved Michael Lehrke2025-04-16, 02:00:19 UTC
