Th22 cells Marker ExpressionCommonIL-22 Expression: + Localization: secreted Analysis strategy: Upon stimulationCitations:[1]Required markerRequiredAHR (Aryl hydrocarbon receptor) Expression: + Localization: intracellularCitations:[1]Suggested markerSuggestedCD4 Expression: +Suggested markerSuggestedCCR10 Expression: +Citations:[1]CD8a Expression: -CD194 (CCR4) Expression: +Citations:[1]CD196 (CCR6) Expression: +Citations:[1]FOXO4 Expression: + Localization: intracellularCitations:[1]Cell/subset InformationTh22 cells produce IL-22, participate in immune responses against bacteria, and promote tissue repair and wound healing.Other NotesNaive CD4+ T cells differentiate into Th22 cells in the presence of IL-6 and IL-23.AliasesT helper type 22TagsT helper lymphocyteT lymphocytelymphoidhematopoieticmesodermInformationCreated Michael Lehrke2025-04-12, 05:56:29 UTCUpdated Michael Lehrke2025-11-06, 05:12:59 UTCApproved Michael Lehrke2025-11-06, 05:12:59 UTC